Synthesis and Antimicrobial Evaluation of Some New Fluoro Formazans
Avinash Taterao Shinde, N. J. Deshmukh, G. D. Kottapalle, S. B. Zangade
J. Pure App. Chem. Res. Vol 5, No 2 (2016), pp. 61-66
Submitted: March 05, 2016     Accepted: April 29, 2016     Published: May 10, 2016
DOI: http://dx.doi.org/10.21776/ub.jpacr.2016.005.02.247

Abstract


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A series of fluoro substituted formazan derivatives has been synthesized from the salt of diazonium chloride & fluoro schiff base in pyridine. The structure of newly synthesized formazans were established based on IR, 1H NMR and mass spectral data. All the synthesized compounds were screened for their antimicrobial activity. Some of the compounds showed very good activity compared to standard drugs against all pathogenic bacteria and fungi.

Keywords : Fluoro-schiff base, Formazans, Diazonium chloride, Antimicrobial activity.
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